Endothelial cell densities are a requirement for patient screening and selection prior to implantation of phakic intraocular lenses
(Intraocular Contact Lenses, or "ICLs").
Without adequate endothelial cell densities, the current ICLs are contraindicated as reflected in the FDA's approved labeling for use of the devices. This clearly highlights the importance of this screening procedure. Endothelial cell densities must be accurately checked preoperatively to ensure that a patient is a suitable candidate, and then should be monitored periodically postoperatively to verify the endothelium's continued health. Although endothelial cell densities can be crudely estimated using card developed in the 1980's, this technique has significant limitations that are now well answered with Konan's specular microscopy technologies:
- High precision and repeatability
- Excellent visualization of even stage +1 / +2 guttata that could significantly skew results
- Analysis of both cell counts and cell morphology changes (morphology is not assessed with a "card").
Changes in morphology can be a very sensitive indicator of corneal stress.
- Unique ability to identify endothelial data location and assess trends over time.
Acquiring endothelial cell count or morphology changes over time from dissimilar locations can present erroneous assumptions on trends analysis.
- Technician administered diagnostic test with full photographic documentation and statistics in only seconds.
Does not require additional physician chair time and eliminates the inherent problems of "card" estimates.
- Important complementary uses for pre-operative assessments of corneal and other anterior segment procedures
- The Gold Standard diagnostic device used for virtually all clinical trials of these types of devices is from Konan.
You deserve the assurance of the collecting the same high quality data to assess and document that the cornea is physiologically adequate to support these surgical interventions.
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Konan Medical provides
the most widely used
endothelial analysis tools
for routine clinical practice,
clinical trials supporting devices
and pharmaceuticals,and
quality eye bank systems to a
majority of the world's premier eye banks
for qualification and analysis of
donor corneal tissue.
Proven experience,
continued product enhancements,
trusted by more physicians
and eye banks than any
other system world wide.
Only from Konan.
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Theodore Perl, MD in "Avoiding Complications with Phakic IOLs", Cataract and Refractive Surgery Today, October 2009 counsels that it "is important to select patients whose endothelial cell density and morphology are normal."
Vance Thompson, MD in "Phakic IOL's Find a Solid Niche" Ophthalmology Management, September 2009 describes the importance of safety data point by requiring "every phakic lens candidate to have a minimum of 3.2 mm anterior chamber depth and a baseline endothelial cell count of more than 2,000."
Visian ICL™, Staar Surgical™, Verisyse™, Abbot Medical Optics™, AcrySof® Cachet™, and ALCON® are trademarks of their respective owners.
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